Determination of urine tumor necrosis factor, IL-6, IL-8, and serum IL-6 in patients with hemorrhagic fever with renal syndrome

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Determination of urine tumor necrosis factor, IL-6, IL-8, and serum IL-6 in patients with hemorrhagic fever with renal syndrome.

OBJECTIVE The aim of this study was to explore the role of cytokines in the pathogenesis of hemorrhagic fever with renal syndrome (HFRS). METHODS Double-antibody sandwich ELISA was used to determine serum interleukin (IL)-6, urine tumor necrosis factor (TNF), IL-6, and IL-8 levels in 56 patients with HFRS. RESULTS Serum IL-6, urine TNF, IL-6, and IL-8 concentrations in HFRS patients were si...

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ژورنال

عنوان ژورنال: The Brazilian Journal of Infectious Diseases

سال: 2012

ISSN: 1413-8670

DOI: 10.1016/j.bjid.2012.10.002